||Dwayne Johnson (Davis Okoye), Naomie Harris (Dr. Kate Caldwell), Malin Åkerman (Claire Wyden), Jeffrey Dean Morgan (Agent Russwell), Jake Lacy (Brett Wyden), Joe Manganiello (Burke), Marley Shelton (Dr. Kerry Atkins), P. J. Byrne (Nelson), Demetrius Grosse (Colonel Blake), Jack Quaid (Connor), Breanne Hill (Amy), Matt Gerald (Zammit), Will Yun Lee (Agent Park), Urijah Faber (Garrick), Bruce Blackshear (Taylor), Mac Wells (Communications Officer), Allyssa Brooke (Radar Officer), Stephen Dunlevy (First MP), Jason Liles (George)
||Primatologist Davis Okoye shares an unshakable bond with George, the extraordinarily intelligent, silverback gorilla who has been in his care since birth. But a rogue genetic experiment gone awry mutates this gentle ape into a raging creature of enormous size. To make matters worse, it’s soon discovered there are other similarly altered animals. As these newly created alpha predators tear across North America, destroying everything in their path, Okoye teams with a discredited genetic engineer to secure an antidote, fighting his way through an ever-changing battlefield, not only to halt a global catastrophe but to save the fearsome creature that was once his friend.